How would a future society, integrated with psychedelics as therapeutic and scientific tools, look and function? As stewards of the Earth, psychedelics may have the capability to help us usher in a positive future where spirituality and the supernatural have returned as an important part of the human experience. What we can learn from indigenous shamanic cultures, that have these medicines integrated into their psycho-spiritual-social cultures, may help us hold on to our humanity in a future when our minds merge with machines.